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SASInstitute SAS Clinical Trials Programming A00-282

A00-282

Exam Code: A00-282

Exam Name: Clinical Trials Programming Using SAS 9.4

Updated: Aug 25, 2026

Q&A Number: 144 Q&As

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A00-282 exam dumps

SASInstitute A00-282 Exam Syllabus Topics:

SectionWeightObjectives
Topic 1: Clinical Trials Data Structures10%- Clinical domain structures
- CDISC standards: SDTM, ADaM
- Define.xml and dataset specifications
Topic 2: Regulatory Submissions5%- Compliance for clinical data reporting
- ICH and FDA guidelines
Topic 3: Macro Programming for Clinical Trials15%- Create and call macros
- Macro variables and parameters
- Debugging macros
Topic 4: Apply Statistical Procedures for Clinical Trials15%- PROC MEANS, FREQ, TABULATE
- Basic statistical analysis for clinical data
Topic 5: Clinical Trials Process5%- Derive programming requirements from protocol and CRF
- Clinical trial lifecycle and protocol
Topic 6: Validate Clinical Trial Data Reporting20%- Programming validation techniques
- Validation principles
- Use PROC COMPARE and log review
Topic 7: Transform or Summarize Clinical Trials Data15%- Data step manipulation
- Aggregation and transposition
- Derive variables and study days
Topic 8: Report Clinical Trials Results10%- PROC REPORT and PROC PRINT
- Produce tables, listings, and figures
Topic 9: Manage Clinical Trials Data5%- Use SQL and dictionary tables
- Access and explore clinical datasets
- Clean, merge, and subset data

SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:

1. This question will ask you to provide a line of missing code. Given the data set RAWBP that is sorted by SUBJECT TEST WEEK:

The following SAS program is submitted:
data bp;
set rawbp;
by subject test week;
retain baseline;
if first.test then baseline = .;
if week = 0 then baseline = value;
else if week > 0 then do;
<insert code here>
end;
run;
Which statement must be added to the program to calculate percent change from baseline?

A) pct_chg = ((value - baseline) /value)*100;
B) pct_chg = ((value - baseline) /baseline)*100;
C) pct_chg = ((baseline - value) /baseline)*100;
D) pct_chg = ((baseline - value) /value)*100;


2. What is the main focus of 21 CFR Part 11?

A) trial protocol requirements
B) trial safety requirements
C) statistical calculation requirements
D) electronic submission requirements


3. How does the code shown below help to validate report output?
data check;
set datlib.medhist;
mh_len = length(trim(mhcom1));
run;
proc freq data=check;
tables mh_len;
run;

A) It writes all values of the mhcom1 variable that are longer than 200 in the results.
B) It shows all the values for the length of mhcom1 in the results.
C) It helps the programmer determine which observation has the longest value for mhcom1.
D) It shows all the values for mhcom1 in the results.


4. This question will ask you to provide lines of missing code.
Given the following SCORE data set:

Variable LOCF contains the imputed score that would replace the missing SCORE value (based on last observation carried forward method).
Which SAS statements complete the program?

A) retain score; if first.subject then LOCF = .; if score ^= . then LOCF = score;
B) LOCF = lag(score); if first.subject then LOCF = .; if score ^= . then LOCF = score;
C) if first.subject then LOCF = .; if score = . then LOCF = lag(score);
D) retain LOCF; if first.subject then LOCF = .; if score ^= . then LOCF = score;


5. Given the following output from the TTEST Procedure: Variable:

What is the t-test p-value?

A) 0.2041
B) 0.3121
C) <.0001
D) 37.49


Solutions:

Question # 1
Answer: B
Question # 2
Answer: D
Question # 3
Answer: B
Question # 4
Answer: D
Question # 5
Answer: C

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