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American Society of Microbiology ABMM Sample Questions:
1. A patient with a history of travel to Southeast Asia presents with fever, severe headache, and altered mental status. CSF analysis reveals lymphocytic pleocytosis and elevated protein, but routine bacterial and viral cultures are negative. Serological testing of CSF is positive for IgM antibodies against Japanese encephalitis virus. The MOST likely mode of transmission for this infection is:
A) Bite of an infected mosquito.
B) Respiratory droplets from an infected individual.
C) Direct contact with infected animals.
D) Ingestion of contaminated food or water.
2. A patient with recent abdominal surgery develops a fever, abdominal pain, and a wound infection. Gram stain of the wound exudate reveals a mixture of Gram-negative rods and Gram-positivebacilli. Anaerobic culture yields a foul-smelling, Gram-negative rod that is bile-esculin positive. The MOST likely organism is:
A) Clostridium perfringens
B) Peptostreptococcus anaerobius
C) Escherichia coli
D) Bacteroides fragilis
3. The human virome, the collection of viruses that reside in and on the human body, is increasinglyrecognized for its role in health and disease. Which of the following statements regarding the human virome is MOST accurate?
A) The human virome is largely independent of the host's immune status.
B) The human virome is primarily composed of pathogenic viruses that cause acute infections.
C) Bacteriophages, viruses that infect bacteria, are a significant component of the human gut virome.
D) The composition of the human virome is relatively stable over time and is not influenced by environmental factors.
4. A clinical microbiology laboratory is using flow cytometry to analyze lymphocyte subsets in a patient with suspected immunodeficiency. Which of the following cell surface markers is typically used to identify helper T cells?
A) CD8
B) CD19
C) CD56
D) CD4
5. Which biosafety level (BSL) is required for clinical laboratory work involving the propagation (culture) of Coccidioides immitis/posadasii?
A) BSL-4
B) BSL-3
C) BSL-2
D) BSL-1
Solutions:
| Question # 1 Answer: A | Question # 2 Answer: D | Question # 3 Answer: C | Question # 4 Answer: D | Question # 5 Answer: B |


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